Sarah Ann R. Anderson, Anna M. Oprescu, Diane Callelo, Andrew Monte, Peter S. Dayan, Yasmin L. Hurd, Alex F. Manini, on behalf of the ToxIC Investigators

Pediatrics Jul 2019, e20182690; DOI: 10.1542/peds.2018-2690

This multi-site US study of adolescents presenting with acute cannabis-related toxicity found that synthetic cannabis use was associated with more frequent central nervous system depression (OR 3.89) and seizures (OR 3.42) than recreational cannabis use.  Users of both types of substance had even greater rates of seizures (OR 4.8)

https://pediatrics.aappublications.org/content/early/2019/07/04/peds.2018-2690