Therapies (including Medication) Archives - Page 3 of 16

Safety and efficacy of agomelatine in children and adolescents with major depressive disorder receiving psychosocial counselling: a double-blind, randomised, controlled, phase 3 trial in nine countries

Feb 4, 2022

Agomelatine is a new medication that, in conjunction with psychosocial counselling, appears to be effective at treating childhood depression. Arango, C., Buitelaar, J. K., Fegert, J. M., Olivier, V., Pénélaud, P. F., Marx, U., ... & Wolańcz...

Pharmacotherapy for trichotillomania

Nov 26, 2021

Trichotillomania (hair pulling) is an infrequent, but potentially significant issue for children, young people and adults. This review of medications found that there was weak evidence for the efficacy of N-acetylcysteine, clomipramine and olanzapine...

NICU music therapy effects on maternal mental health and preterm infant’s emotional arousal

Nov 26, 2021

This Brazilian study found that music therapy in the neonatal intensive care unit (NICU) improved maternal anxiety, depression and stress, as well as infant observations such as heart rate and oxygen saturation. Palazzi, A., Meschini, R., & Pi...

New generation antidepressants for depression in children and adolescents: a network meta-analysis

Jun 18, 2021

This network meta-analysis of 26 trials identified significant gaps in the evidence base regarding the treatment of childhood depression with newer generation antidepressants. Fluoxetine, sertraline, escitalopram and duloxetine appeared to...

A Meta-analytic Review: Psychological Treatment of Subthreshold Depression in Children and Adolescents

Jun 18, 2021

Subthreshold depression has been previously shown to be as functionally impairing as major depression. This systematic review found an overall effect size of 0.38 and a number-needed-to-treat (NNT) of 8.4 for psychological (primarily CBT-b...

Practitioner Review: Pharmacological treatment of attention-deficit/hyperactivity disorder symptoms in children and youth with autism spectrum disorder: a systematic review and meta-analysis

Jun 18, 2021

Attention Deficit and Hyperactivity Disorder (ADHD) commonly occurs in children with autism. This systematic review shows that first-line treatment with methylphenidate and atomoxetine is appropriate and tolerable for this group. ...

α2-Adrenergic Agonists or Stimulants for Preschool-Age Children With Attention-Deficit/Hyperactivity Disorder

Jun 18, 2021

This retrospective review of heath records of almost 500 children found that 66% of pre-school children who received treatment for Attention Deficit and Hyperactivity Disorder (ADHD) with alpha-adrenergic agonists (such as clonidine) and 78% of those...

A Randomized Controlled Trial of Combinatorial Pharmacogenetics Testing in Adolescent Depression

Jun 18, 2021

Despite enthusiasm for the prospect of treatment being guided by pharmacogenomics rather than clinical judgement, this randomised controlled trial showed that there was no clinical benefit from this new approach. Whether this is related to current ph...

Efficacy of attachment-based family therapy compared to treatment as usual for suicidal ideation in adolescents with MDD

Feb 26, 2021

Waraan L, Rognli EW, Czajkowski NO, Mehlum L, Aalberg M. Attachment Based Family Therapy (ABFT) has been proposed as a suitable treatment for reducing suicidal ideation in young people with depression. This study of 60 young people did not find th...

Effectiveness of Transdiagnostic Cognitive-Behavioral Psychotherapy Compared With Management as Usual for Youth With Common Mental Health Problems

Feb 26, 2021

Jeppesen P, Wolf RT, Nielsen SM, et al. This randomised controlled trial demonstrates that transdiagnostic cognitive behaviour therapy in more effective than treatment as usual in addressing common emotional and behavioural problems experienced by...

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