Cannabinoids for the treatment of mental disorders and symptoms of mental disorders: a systematic review and meta-analysis
Black N, Stockings E, Campbell G, Tran LT, Zagic D, Hall WD, Farrell M, Degenhardt L. Lancet Psychiatry. 2019 Dec;6(12):995-1010. doi: 10.1016/S2215-0366(19)30401-8. Epub 2019 Oct 28.
Despite calls to legalise cannabinoids for everything from the treatment of pain to cancer, this review demonstrates that they are more likely to lead to harm than good when it comes to the treatment of mental disorders. There was only low quality evidence regarding their effectiveness for treating anxiety and their use was associated with a higher rate of drop-out due to adverse effects.