Comparative efficacy and acceptability of antidepressants, psychotherapies, and their combination for acute treatment of children and adolescents with depressive disorder: a systematic review and network meta-analysis
Zhou X, Teng T, Zhang Y, et al. Comparative efficacy and acceptability of antidepressants, psychotherapies, and their combination for acute treatment of children and adolescents with depressive disorder: a systematic review and network meta-analysis. Lancet Psychiatry. 2020;7(7):581-601. doi:10.1016/S2215-0366(20)30137-1.
This systematic review and network meta-analysis of 71 studies found that a combination of fluoxetine and cognitive behaviour therapy is best for the treatment of moderate-severe adolescent depression.