Psychotherapy for Depression Across Different Age Groups: A Systematic Review and Meta-analysis.
Cuijpers P, Karyotaki E, Eckshtain D, et al. Psychotherapy for Depression Across Different Age Groups: A Systematic Review and Meta-analysis. JAMA Psychiatry. 2020;77(7):694–702. doi:10.1001/jamapsychiatry.2020.0164.
Despite concerns about side effects of antidepressant medication and recommendations to use talking therapies (psychotherapies) first line to treat childhood depression, this systematic review and meta-analysis found that the effect sizes for psychotherapies in children (g=0.35) were less than those of adolescents (g=0.55), young adults (0.98) and middle-aged adults (g=0.77), suggesting that clinicians need to balance the likelihood of clinical effects with that of adverse effects.