Treatment of Bipolar Depression With Minocycline And/Or Aspirin: An Adaptive, 2×2 Double-Blind, Randomized, Placebo-Controlled, Phase IIA Clinical Trial
JB Savitz et al. Transl Psychiatry 8 (1), 27. 2018 Jan 24
This randomised controlled trial showed that Minocycline and aspirin may be useful adjunctive treatments for addressing bipolar depression and that inflammatory modulators such as interleukin 6 (IL-6) may be relevant to their action. Although this is an adult study, it may be of relevance to young people experiencing this condition.